Antitumor Drug Radiation Interactions by Bridget T. Hill

Cover of: Antitumor Drug Radiation Interactions | Bridget T. Hill

Published by CRC-Press .

Written in English

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Subjects:

  • Oncology,
  • Radiotherapy,
  • Health/Fitness,
  • Cancer Chemotherapy,
  • Medical / Nursing,
  • Radiology,
  • Pharmacology,
  • Medical / Oncology,
  • Antineoplastic agents,
  • Adjuvant therapy,
  • Cancer,
  • Chemotherapy

Book details

The Physical Object
FormatHardcover
Number of Pages284
ID Numbers
Open LibraryOL8260441M
ISBN 100849346207
ISBN 109780849346200

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Jan 10,  · This volume reviews the experimental data on drug-radiation interactions. Special emphasis is placed on clinically-useful antitumor drugs.

Particular reference is made to appropriate timing, concentration and sequencing of drug-radiation fredjaillet.com by: This volume reviews the experimental data on drug-radiation interactions.

Special emphasis is placed on clinically-useful antitumor drugs. Particular reference is made to appropriate timing, concentration and Antitumor Drug Radiation Interactions book of drug-radiation fredjaillet.com by: This volume reviews the experimental data on drug-radiation interactions. Special emphasis is placed on clinically-useful antitumor drugs.

Particular reference is made to appropriate timing, concentration and sequencing of drug-radiation fredjaillet.com: Bridget T. Hill. Get this from a library. Antitumor drug-radiation interactions. [Bridget T Hill; Angela S Bellamy;] -- This volume reviews the experimental data on drug-radiation interactions.

Special emphasis is placed on clinically-useful antitumor drugs. Particular reference is made to appropriate timing. May 23,  · Antitumor Drug Radiation Interactions. This volume reviews the experimental data on drug-radiation interactions.

Special emphasis is placed on clinically-useful antitumor drugs. Particular reference is made to appropriate timing, concentration and sequencing of drug-radiation combinations. It includes discussions. This volume reviews the experimental data on drug-radiation interactions.

Special emphasis is placed on clinically-useful antitumor drugs. Particular reference is made to appropriate timing, concentration and sequencing of drug-radiation Antitumor Drug Radiation Interactions book. Get this from a library. Antitumor Drug Radiation Interactions. [Bridget T Hill; Angela S Bellamy] -- "This volume reviews the experimental data on drug-radiation interactions.

Special emphasis is placed on clinically-useful antitumor drugs. Particular reference is made to appropriate timing. Antitumor Drug-Radiation Interactions. the antitumor drug mitomycin C. Expression of the bacterial mcrA gene in mammalian Chinese hamster ovary cells causes profound resistance to mitomycin C.

Drug absorption and clearance are influenced by multiple factors, including age, sex, metabolism, disease state, organ function, drug-to-drug interactions, genetics, and obesity, which has a major impact on the actual concentration of the drug in the person's fredjaillet.com names: chemo.

Useful Interactions between 5-Fluorouracil and Radiation in Man: 5-Fluorouracil as a Radiosensitizer 87 John E. Byfield Chapter 6 Interactions between Microtubule Inhibitors and Ionizing Radiation Guy Storme, W. Distelmans, W. De Neve, and M. Mareel Chapter 7 Interactions between Mitomycin C and Radiation Sara Rockwell and Alan C Sartorelli.

Little is known about the interactions of cytotoxic drugs and radiation at the subcellular or molecular levels. Although much is known about the mechanisms of action of the various classes of drugs, such as alkylating agents, antimetabolites, plant alkaloids, and antibiotics, little is known about specific drug-radiation interactions.

Interactions between clinically effective antitumor drugs and radiation in experimental systems Author links open overlay panel Angela S. Bellamy ∗ Bridget T. Hill Show moreCited by: Clinical fundamentals for radiation oncologists This book is not designed to provide prescriptive guidelines for.

Antitumor Drug-Radiation Interactions. Sep 01,  · Synergistic antitumor effects of radiation and proteasome inhibitor treatment in pancreatic cancer through the induction of autophagy and the downregulation of TRAF6.

Chiu HW(1), Lin SW(2), Lin LC(3), Hsu YH(4), Lin YF(1), Ho SY(5), Wu YH(6), Wang YJ(7).Cited by: Nov 20,  · PURPOSE: The purpose of this study was to evaluate whether endostatin, an antiangiogenic cleavage fragment of collagen XVIII, enhances the Cited by: Osmium Complexes with Azole Heterocycles as Potential Antitumor Drugs Antitumor Drug – Anticancer Drug | SpringerLink Skip to main content Skip to table of contents.

Learn more about Melatonin uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Melatonin. The combination of radiation therapy and immunotherapy holds enticing promise as a strategy for cancer treatment.

Preclinical studies have shown that radiation may act synergistically with immunotherapy to enhance or broaden antitumor immune responses, in part due to radiation-induced phenotypic alterations of tumor cells that render them more susceptible to immune-mediated fredjaillet.com by: These chemotherapy medicines are called antitumor antibiotics.

These antibiotics are not like the antibiotics used to treat infections. Instead, these antitumor antibiotics interfere with the DNA inside cells.

This slows or stops cancer cells from growing and keeps them from multiplying. (Drug Reference is not available in all systems.). Anticancer drug, also called antineoplastic drug, any drug that is effective in the treatment of malignant, or cancerous, disease.

There are several major classes of anticancer drugs; these include alkylating agents, antimetabolites, natural products, and hormones. In addition, there are a number of. Mar 09,  · This is a question for your radiation oncologist.

Please ask him or her about any drug or supplement (if you're taking any) interactions and I would check with your regular oncologist as well. Everybody's treatment is a little different, so again you really need to ask the radiation oncologist. Good luck and best wishes. The study of tumour resistance to anticancer drugs has been the subject of many publications since the initial discovery of the phenomenon by J.

Burchenal and colleagues in Many papers have been published since then reporting development of resistance to most of the well-known. Antitumor Drug Resistance by Brian W. Fox,available at Book Depository with free delivery worldwide.

Advances in Radiation Biology, Volume 11, provides an overview of the state of knowledge in the field of radiation biology. The book contains eight chapters and begins with a study on ADP-ribose in DNA repair. This is followed by separate chapters on the inhibition of DNA repair; the. Oct 22,  · Advances in Radiation Biology, Volume 11, provides an overview of the state of knowledge in the field of radiation biology.

The book contains eight chapters and begins with a study on ADP-ribose in DNA fredjaillet.com Edition: 1. Development of clinically useful antitumor drug combinations has been largely empirical and there is a pressing need to evaluate Drug Combination Testing with in Vitro Clonal Cultures.

Authors; Authors and affiliations Steel GG () Terminology in the description of drug-radiation interactions. Int J Rad Oncol Biol Phys 5: – Cited by: 5.

Antitumor definition is - preventing or inhibiting the formation or growth of tumors: anticancer. How to use antitumor in a sentence. The molecular processes of drugs from cellular uptake to intracellular distribution as well as the intracellular interaction with the target molecule are critically important for the development of new antitumor drugs.

In this work, we have successfully developed a label-free surface-enhanced Raman scattering (SERS) technique to monitor and visualize the metabolism of antitumor drug 6 Cited by: In fact, a major cause of failure of anticancer drug development is lack of efficacy.

Genetic interactions among various cancer-related pathways often provide redundant input from parallel and/or cooperative pathways that drives and maintains survival environments for cancer cells, leading to low efficacy of single-target fredjaillet.com by: Drug-induced ACD is also a primary mechanism for antitumor drugs.

Therefore, autophagy has been widely studied as a drug target in antitumor research. First, this new research strategy of old drugs provides ideas for autophagy-targeted drug discovery.

arsenic-trioxide and ionizing-radiation combination treatment on glioma cells also Author: Hai Zhang, Zhinan Chen. Historical Perspective. Radiosensitization and chemosensitization are each complex concepts that have many different interpretations and have been used to describe a variety of interactions.

1,2 The combination of irradiation and chemotherapy for mutual or even simultaneous sensitization increases the intricacies of these interactions. For example, over years ago radiation treatment and.

Jul 02,  · If this drug is used during pregnancy, or if a woman becomes pregnant while taking Gemzar, the patient should be apprised of the potential hazard to a fetus [see Use In Specific Populations].

Exacerbation Of Radiation Therapy Toxicity. Gemzar is not indicated for use in combination with radiation therapy. antitumor: (ăn′tĭ-to͞o′mər, -tyo͞o′-) also antitumoral (-mər-əl) adj.

Anticancer. Learn more about Kefir uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Kefir. Synergistic antitumor effects of radiation and proteasome inhibitor treatment in pancreatic cancer through the induction of autophagy and the downregulation of TRAF6.

Hui Wen Chiu, Shu Wen Lin, Li Ching Lin, Yung Ho Hsu, Yuh Feng Lin, Sheng Yow Ho, Yuan Hua Wu, Ying Jan fredjaillet.com by: Medscape - Indication-specific dosing for China chlorella, green algae, kyochlorella, sun chlorella granules (chlorella), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Antitumor drug nogalamycin binds DNA in both grooves simultaneously: molecular structure of nogalamycin-DNA complex Radiation Chemistry, Photochemistry, and Photographic and Other Reprographic Processes Mechanism of DNA-drug interactions.

Prakash Prabhakar, Arvind M. Kayastha. Applied Biochemistry and Biotechnology 47 (1), Cited by: X from PHEA–DOX in S ascites was faster than that in mouse serum or in buffer solutions.

An in-vivo antitumor study revealed that PHEA–DOX was more effective than DOX against solid S tumor after intraperitoneal injection at the same dose of 10 or 15 mg (DOX eq.)/kg, respectively.

At a high dose of 28 mg (DOX eq.)/kg, which was lethal for free DOX to mice, PHEA–DOX could inhibit Strategies to attenuate drugs and radiation toxicity include dosage optimization, synthesis, and the use of analogues having lower toxicity or a combined therapy with antioxidants.

Clinical and experimental trials have been directed toward employing various antioxidant agents to ameliorate drug- and radiation-induced liver fredjaillet.com by: 4. Platinum (Pt)-based antitumor agents have been effective in treating many human malignancies. Drug importing, intracellular shuffling, and exporting—carried out by the high-affinity copper (Cu) transporter (hCtr1), Cu chaperone (Ato x1), and Cu exporters (ATP7A and ATP7B), respectively—cumulatively contribute to the chemosensitivity of Pt drugs including cisplatin and carboplatin, but not Cited by: 6.

Dec 21,  · Targeted drugs have augmented the cancer treatment armamentarium. Based on the molecular specificity, it was initially believed that these drugs had significantly less side effects. However, currently it is accepted that all of these agents have their specific side effects.

Based on the given multimodal approach, special emphasis has to be placed on putative interactions of conventional Author: Maximilian Niyazi.Unique considerations of this patient population must be taken into account when designing the anesthetic plan, including the direct effects of the tumor, impact of the surgical procedure, effects of chemotherapy and radiation therapy, drug–drug interactions between chemotherapeutic agents and anesthetic drugs, pain syndromes, and psychologic Cited by: Aug 21,  · Ionizing radiation can therefore activate or guide drug delivery to neoplasms with greater precision compared with other forms of energy deposition into tissue.

Table lists the mechanisms by which ionizing radiation can either guide or activate drug delivery within cancer. The first general principle is the use of monochromatic X-rays to.

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